Because these tumors are so rare, no specific screening measures seem appropriate unless the individual has other first-degree relatives with one of the above syndromes. A physician should suspect some type of adrenal tumor, however, if there are signs of Cushing's syndrome or high blood pressure in the presence of potassium deficiency, as well as unexplained hypertension, especially if it is severe or in patients with a family history of the above risk factors .
Patients with medullary thyroid cancer and hypertension always should be screened for pheochromocytoma prior to stressful procedures.
